A) Leukocoria
Leukocoria (a white appearance to the pupil instead of the normal red reflex) is associated with retinoblastoma. The other signs are all associated with neuroblastoma, a tumor that arises from primitive sympathetic ganglion cells and can be located anywhere throughout the sympathetic nervous system. The most common location is the adrenal gland. Opsoclonus is rapid repeated eye movements, and myoclonus is repetitive muscle jerks. Other findings seen with neuroblastoma include: abdominal mass, constipation, back pain / weakness (spinal cord compression), bladder dysfunction, nontender subcutaneous nodules, paraneoplastic syndromes such as secretory diarrhea, fever, weight loss, bone pain, anemia, different colored iridia, hypertension.
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November 15, 2023 at 1:19 pm
A) Leukocoria
Leukocoria (a white appearance to the pupil instead of the normal red reflex) is associated with retinoblastoma. The other signs are all associated with neuroblastoma, a tumor that arises from primitive sympathetic ganglion cells and can be located anywhere throughout the sympathetic nervous system. The most common location is the adrenal gland. Opsoclonus is rapid repeated eye movements, and myoclonus is repetitive muscle jerks. Other findings seen with neuroblastoma include: abdominal mass, constipation, back pain / weakness (spinal cord compression), bladder dysfunction, nontender subcutaneous nodules, paraneoplastic syndromes such as secretory diarrhea, fever, weight loss, bone pain, anemia, different colored iridia, hypertension.