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Question: Derm
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Which of the following is true about erythema multiforme major, Stevens-Johnson syndrome, and toxic epidermal necrolysis?
Kelly October 17, 2017 - 10:17 pm
C. Drugs are the most common underlying cause of SJS/TEN, but infections such as herpes or mycoplasma are more common triggers of EM major.
Common triggers of EM include herpes, mycoplasma, other infections such as hepatitis, vulvovaginal candidiasis, and to a lesser extent drugs/medications. In contrast, SJS and particularly TEN are commonly a drug-induced reaction. High risk drugs include several anticonvulsants, some antiretrovirals, TMP-SMX, sulfasalazine, and allopurinol.