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You are seeing a 7 year old boy who presents with dark coca-cola colored urine and puffy eyes. You suspect glomerulonephritis. Which of the following is NOT consistent with post-streptococcal glomerulonephritis (the most common cause of acute nephritis in children worldwide)?
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January 13, 2022 at 4:13 pm
) Elevated C3 and CH50
The peak age for post-streptococcal glomerulonephritis is 2-12 years and it is twice as common in boys than girls. It typically occurs 1-2weeks after a GAS throat infection, or 3-6 weeks after a GAS skin infection. Common presenting findings are hematuria (red to brown colored, often described as tea-colored or coca cola-colored), hypertension, edema (especially noted periorbitally in the mornings), and nonspecific malaise. Lab findings include hematuria and proteinuria, and evidence of strep infection (e.g. positive antigen test or culture or elevated ASO titer). Renal function tests should be checked. 90% of patients acutely have low C3 and CH50.