1 Question: Impetigo (Click the link to comment and to vote – voting not working through email, sorry!) Which of the following topical antibiotics has the least efficacy against impetigo? (see pictures of impetigo here and a short article here) Anonymous VoteSign in with WordPressWhich of the following topical antibiotics has the least efficacy against impetigo?A) NeomycinB) BacitracinC) Polymyxin BD) MupirocinE) Retapamulinvote×Username or Email AddressPasswordLog In DermIDPharm pemsou5_wp • March 5, 2019 ↞ Previous PostQuestion: Normals Next Post ↠Interpreting the VBG
Kelly March 5, 2019 - 11:47 am
C) Polymyxin B
Polymyxin B has efficacy against gram negative organisms only. While bacitracin and neomycin have some efficacy against gram positive and gram negative organisms, they are inferior to mupirocin for treatment of impetigo, and are not recommended. Additionally, neomycin has a high rate of causing contact dermatitis. Mupirocin and Retapamulin are both indicated for treatment of impetigo, and mupirocin has the advantage of treating MRSA. Retapamulin may be efficacious for some organisms resistant to mupirocin but is expensive. Mupriocin and Retapamulin are prescription, while the others are available over the counter, often in combination with each other. Confusion may arise because a brand name of mupirocin is Bactroban, which can be confused with Bacitracin.