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An adolescent is brought in intoxicated with history of drinking large amounts of alcohol at a dorm party. He vomited multiple times at the scene and on arrival to the ED. Initial labs and CXR are normal except for an ETOH level of 390. He is protecting his airway, arousable with deep stimulation, and hemodynamically stable, so the decision is to observe him on a monitor while he slowly sobers up, and then reevaluate him for discharge. However, 2 hours later he is requiring 5L O2 by non-rebreather to maintain an O2 saturation of 97%. He does not show significant respiratory distress or apnea, and a venous blood gas does not reveal CO2 retention or significant acidosis.