D) A rise in beta-HCG of < 53% in 48 hours confirms abnormal pregnancy
While the “discriminatory zone” of 1000-2000 mIU/mL is when clinicians expect to be able to see evidence of intrauterine pregnancy (IUP) on transvaginal ultrasound (TVUS), correlation is not perfect – patients with higher beta-HCG may have a viable pregnancy yet no signs of IUP on TVUS, and patients with beta-HCG < 1000 may still show evidence of IUP on TVUS. There are rare cases of negative urine pregnancy test and ectopic (false negatives for various reasons). About half of women with ectopic have a known risk factor. Rarely, heterotopic pregnancy can occur, which is an IUP and an ectopic pregnancy; this is more common in those who have undergone assisted reproduction.
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January 28, 2020 at 4:03 pm
D) A rise in beta-HCG of < 53% in 48 hours confirms abnormal pregnancy
While the “discriminatory zone” of 1000-2000 mIU/mL is when clinicians expect to be able to see evidence of intrauterine pregnancy (IUP) on transvaginal ultrasound (TVUS), correlation is not perfect – patients with higher beta-HCG may have a viable pregnancy yet no signs of IUP on TVUS, and patients with beta-HCG < 1000 may still show evidence of IUP on TVUS. There are rare cases of negative urine pregnancy test and ectopic (false negatives for various reasons). About half of women with ectopic have a known risk factor. Rarely, heterotopic pregnancy can occur, which is an IUP and an ectopic pregnancy; this is more common in those who have undergone assisted reproduction.